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LEGAL DISCLAIMER
Most people don’t even think about growth hormone unless they have been diagnosed with a growth hormone deficiency. While growth hormone is most often associated with growth spurts during childhood and adolescence, it is also responsible for a myriad of activities and processes when it comes to body functions. In the event that the body doesn’t produce enough natural growth hormone on its own, synthetic growth hormone might be recommended in the form of injections. What’s the difference? Click here to buy HGH online now.
Table of Contents
Natural Growth Hormone Booster
A healthy body creates adequate levels of natural growth hormone. Growth hormone is manufactured in the pituitary gland, located in the brain. Known as the master gland, the pituitary is responsible for maintaining the function as well as secretions of numerous hormone glands found within the endocrine system.
In turn, the pituitary gland receives its instructions to either increase or decrease a particular hormone through messages sent from the hypothalamus gland. The hypothalamus is responsible for the maintenance of fluids and homeostasis in the body.
It regulates our body temperature, helps to regulate sleep and waking cycles, sensations of hunger or satiety, and levels of reproductive hormones.
When the hypothalamus senses that growth hormone levels are low, it sends instructions to the pituitary gland through neurohormone chemical messengers (growth hormone-releasing hormone or GHRH) to increase production and secretion.
If the hypothalamus senses the levels are adequate and wants the pituitary to stop manufacturing growth hormone, it sends a different neurohormone known as somatostatin to decrease or halt production.
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Growth hormone influences more than just the length of bones and their strength. It is a peptide hormone designed to encourage cellular growth, regeneration, and reproduction. It is also heavily involved in metabolism of fats and lipids, body composition, and ratio of lean muscle mass to fat mass in the body.
In the event that the hypothalamus or the pituitary gland is malfunctioning, defective, diseased or in any way injured, hormone production, secretions, and balances can be affected. In cases where the pituitary gland fails to create adequate levels of growth hormone, synthetic growth hormone injections may be considered as a treatment option. Find out more here.
What Are Natural Growth Hormone Supplements Made Of?
Today, over two-dozen brands of synthetic growth hormone (Somatropin) are available on the market. Most forms are designed to be identical to natural HGH in regard to the presence of 191 amino acids and its chemical structure.
It is designed using recombinant DNA technology (rDNA). Somatropin mirrors endogenous or body-produced growth hormone manufactured in the pituitary.
Some types of synthetic growth hormone differ from natural growth hormone in its development in the lab. For example, Serostim is manufactured by using a mammalian cell line known as mouse C127 modified by the HGH gene addition.
Genotropin is manufactured by synthesizing a strain of E.coli that’s been modified with a human growth hormone gene.
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Recombinant DNA technology involves the creation or use of DNA molecules that have been created using genetic recombination (think cloning) to morph together genetic materials from a number of sources. This type of DNA technology is possible because the molecules found in any organism in the world share the same DNA chemical structure and only differ in their nucleotide sequences.
At its basic definition, recombinant DNA is a portion of DNA that has been created in a lab by combining a minimum of two strands of DNA from different sources. Recombinant DNA technologies are used in a wide variety of pharmaceutical, biotechnology, research, and medical processes, treatments, and technologies. Before this natural growth hormones had to be extracted.
Is Synthetic Growth Hormone Harmful?
When taken as instructed for medical purposes, synthetic growth hormone injections are relatively safe. Therapies are carefully monitored by a physician to watch for any side effects or adverse reactions. Injections can cause a number of side effects that range from mild to severe.
Age, weight, and medical conditions can also have an effect on the efficacy as well as potential for side effects or adverse reactions. Many natural growth hormone supplements for children or adults are also effective but much safer. Deer antler spray for sale at GNC is one that works.
Use for nonmedical reasons can increase the risk of side effects. Unfortunately, since its creation in the 1980s, synthetic HGH and steroids have been misused and often abused by athletes and bodybuilders wishing to reap the benefits of growth hormone to accelerate the growth of muscles and to enhance physical performance.
Injecting HGH when levels of natural growth hormone are already adequate can contribute to a number of potentially disturbing effects on the body. Doing so can also interfere with or nullify the function of other hormones in the body.
In the event that levels are low, check with a doctor about options. Not everyone diagnosed with a deficiency is a good candidate for HGH therapy. Sometimes eating natural growth hormone foods is enough to grow taller or for bodybuilding.
References
- Serostim – Highlights of Prescribing Information. EMD Serono.
- GENOTROPIN- somatropin highlights of prescribing information. Pfizer Labeling.
- Ehrnborg C, Rosén T. Physiological and pharmacological basis for the ergogenic effects of growth hormone in elite sports. Asian J Androl. 2008 May;10(3):373-83. doi: 10.1111/j.1745-7262.2008.00403.x. Review.
- Rickenlund A, Thorén M, Nybacka A, Frystyk J, Hirschberg AL. Effects of oral contraceptives on diurnal profiles of insulin, insulin-like growth factor binding protein-1, growth hormone and cortisol in endurance athletes with menstrual disturbance. Hum Reprod. 2010 Jan;25(1):85-93. doi: 10.1093/humrep/dep350.
- Jacobson BH. Effect of Amino Acids on Growth Hormone Release. Phys Sportsmed. 1990 Jan;18(1):63-70. doi: 10.1080/00913847.1990.11709950.
- Palmeiro CR, Anand R, Dardi IK, Balasubramaniyam N, Schwarcz MD, Weiss IA. Growth hormone and the cardiovascular system. Cardiol Rev. 2012 Jul-Aug;20(4):197-207. doi: 10.1097/CRD.0b013e318248a3e1. Review.
- Banfi G, Marinelli M, Roi GS, Colombini A, Pontillo M, Giacometti M, Wade S. Growth hormone and insulin-like growth factor I in athletes performing a marathon at 4000 m of altitude. Growth Regul. 1994 Jun;4(2):82-6.
- Dobrza?ski T, Zurowski S, Graban W. Chromoendocrinological studies in athletes. IV. Multiple hormonal responses to submaximal muscular exercise. Acta Physiol Pol. 1981 Sep-Oct;32(5):529-36.
- Galy O, Chamari K, Peyreigne C, Mercier J, Hue O. Sequential exercise in triathletes: variations in GH and water loss. PLoS One. 2014 Apr 24;9(4):e96145. doi: 10.1371/journal.pone.0096145.
- Ehrnborg C, Lange KH, Dall R, Christiansen JS, Lundberg PA, Baxter RC, Boroujerdi MA, Bengtsson BA, Healey ML, Pentecost C, Longobardi S, Napoli R, Rosén T; GH-2000 Study Group.. The growth hormone/insulin-like growth factor-I axis hormones and bone markers in elite athletes in response to a maximum exercise test. J Clin Endocrinol Metab. 2003 Jan;88(1):394-401.
- Adiyaman P, Ocal G, Berbero?lu M, Evliyao?lu O, Aycan Z, Cetinkaya E, Bulca Y, Ersöz G, Akar N. Alterations in serum growth hormone (GH)/GH dependent ternary complex components (IGF-I, IGFBP-3, ALS, IGF-I/IGFBP-3 molar ratio) and the influence of these alterations on growth pattern in female rhythmic gymnasts. J Pediatr Endocrinol Metab. 2004 Jun;17(6):895-903.
- Chung L, Clifford D, Buckley M, Baxter RC. Novel biomarkers of human growth hormone action from serum proteomic profiling using protein chip mass spectrometry. J Clin Endocrinol Metab. 2006 Feb;91(2):671-7.
- Cox HD, Rampton J, Eichner D. Quantification of insulin-like growth factor-1 in dried blood spots for detection of growth hormone abuse in sport. Anal Bioanal Chem. 2013 Feb;405(6):1949-58. doi: 10.1007/s00216-012-6626-y.
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